Silicone materials have been subject to dozens of scientific studies showing that they are safe for human health. (When used for their intended purposes, as with all products.) D4, D5 and D6 are among the most extensively studied materials currently used in consumer and industrial applications and because of their versatility and safety profile, they are used to create hundreds of applications that improve people’s lives every day.
Risk evaluations have been conducted by regulatory agencies such as Health Canada, Australia Departments of Environment and Health, by UK regulatory bodies, and by expert scientific panels such as the Cosmetic Ingredient Review and the EU Scientific Committee on Consumer Safety. All of these risk assessments concluded that there is no risk to human health from silicone materials when used appropriately.
In Canada, government health officials used a risk-based approach to evaluate specific siloxanes and determined there was no indication of any risk to children or adults. According to Health Canada, “Siloxanes were evaluated for risks to human and environmental health under the Chemicals Management Plan. An analysis of exposure through cosmetic products showed that the substances do not present a risk to human health as currently used.”
Australia also conducted a human health assessment for the siloxanes D4, D5 and D6. The Australia Department of Health “found that D4 posed no risk to human health and that current risk management measures are considered adequate to protect public and workers’ health and safety. Australia’s regulatory officials noted that no further assessment of D4 is currently required.”
Australia’s human health assessment of D5 stated, “There are no critical health effects for the chemical.” Australia concluded that “Overall, the MoS/MoE [Margin of Safety/Margin of Exposure] estimates indicate that the chemical, when used in consumer products, does not pose a human health risk.” As a result, no further assessment is currently required for D5.
Similarly, the Australian assessment concluded that there are no critical health effects for D6. They stated that “…given the low bioavailability and low toxicity of the chemical, significant public risk is not expected.” The assessment also reported, “Based on the available data, the chemical is not likely to be hazardous to human health.” Australia found that no further assessment of D6 is required.
In addition, the United States Cosmetic Ingredient Review concluded there is no risk to human health in cosmetic applications.
The silicones industry will continue to be at the forefront of research to provide even greater scientific understanding of the health and environmental safety of silicone materials used in consumer and industrial applications.